In the 17th century, the Theatine Fathers transformed the basilica according to the Baroque taste then prevailing. Latin-cross plan, divided into three naves, the church is adorned with valuable works, mostly depicting moments in the life of the saint and the history of Sorrento. Of particular interest are the four paintings by Giacomo del Po above the wooden chancel of the apse. A silver statue of Antoninus is dated 1564. The saint's remains are in the crypt below, known as the Succorpo, adorned with valuable painted votive offerings donated by sailors. In the sacristy are numerous works of art, a rare majolica floor and 18th-century nativity scene shepherds.
From Piazza Sant'Antonino, a few steps further on, one finds oneself pleasantly surrounded by the flowering pergolas of Piazza Tasso, Sorrento's good living room, on one side of which stands a statue dedicated to the celebrated author of "Gerusalemme Liberata."
